Selenium sulphide in the treatment of scalp seborrheic dermatitis*

*Szponzorált közlemény

Abstract

Seborrheic dermatitis is an inflammatory condition n the skin with increased sebum production and peeling. Most frequent localisations are the scalp, the eyebrows and the nose. The microbiome of the affected skin area is altered compared to normal skin, with a different number and proportion of fungal and bacterial species. Treatment aimsto restore the normal microbiome. In mild to moderate cases, selenium sulphide may be recommended as an adjunct therapy to the widely used ketoconazole. Selenium sulphide also reduces the number of relapses. According to our knowledge the antimicrobial effect of selenium sulphide is based on the reducction of the abnormally elevated Staphylocossus bacteria count, in addition to the reduction of the Malassezia colonisation of the seborrhoeic skin, thus helping to restore the skin homeostasis.