Full mouth rehabilitation, complete dental prosthesis fabricated for an acromegally patient in semi-adjustable articulator
Case report
Abstract
Acromegaly is a severe systemic disease that is caused by increased growth hormone (GH) and IGF-1 production. Clinical manifestations of the disease include increased skeletal growth and soft tissue proliferation with metabolic, cardiovascular and respiratory comorbidities. Due to the slow change in the patients’ appearance, diagnosis can take decades. This case presents a full mouth rehabilitation for the patient with acromegaly. During the treatment, the implantation was contraindicated due to multiple systemic diseases; therefore, a conventional complete denture was made in a semi adjustable articulator. Due to the extreme enlargement of the patient’s jaws, the treatment was a unique and an exciting professional experience.
References
Colao A, Ferone D, Marzullo P, Lombardi G: Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 2004; 25: 102. https://doi.org/10.1210/er.2002-0022
Fábián T, Götz Gy, Kaán M, Szabó I: A fogpótlástan alapjai. Semmelweis Kiadó 2001; 356–360.
Davi M V, Dalle Carbonare L, Giustina A, Ferrari M, Frigo A: Sleep apnoea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. Eur J Endocrinol 2008; 159 (5), 533–540. https://doi.org/10.1530/EJE-08-0442
Drange MR, FramNR, VHerman-Bonert, SMelmed: Pituitary tumor registry: a novel clinical resource. J Clin Endocrinol Metab 2000; 85 (1), 168–174. https://doi.org/10.1210/jc.85.1.168
GóthM, Korbonits M Acromegalia In: Leövey A, Nagy VE, ParaghGy, et al: Az endokrin és anyagcsere-betegségek kézikönyve. Medicina Kiadó 2017, 73–96.
GóthM, Kovács L, Dénes J, Hubina E: Acromegalia. Orvostovábbképző szemle 2019; 4.
Hermann P, Szentpétery A: Gnatológia. Semmelweis Kiadó 2018; 117, 165–169, 234–240.
Kaltsas GA, Mukherjee JJ, Jenkins PJ, et al: Menstrual irregularity in women with acromegaly. J Clin Endocrinol Metab 1999; 84: 2731. https://doi.org/10.1210/jcem.84.8.5858
Kreitschmann-Andermahr I, Kohlmann J2, Kleist B3, Hirschfelder U4, Buslei R5, Buchfelder M3, SiegelS2.: Orodental pathologies in acromegaly. Endocrine 2018 May; 60 (2): 323–328. doi: 10.1007/s12020-018-1571-y. Epub 2018 Mar 8. https://doi.org/10.1007/s12020-018-1571-y
Lugo, L. Pena, FCordido: Clinical manifestations and diagnosis of acromegaly. Int J Endocrinol 2012, 540398. https://doi.org/10.1155/2012/540398
Melmed S: Medical progress: acromegaly. N Engl J Med 2006; 355 (24), 2558–2573. https://doi.org/10.1056/NEJMra062453
Melmed S: Acromegaly pathogenesis and treatment. J Clin Invest 2009; 119: 3189–3202. https://doi.org/10.1172/JCI39375
MolitchME. Clinical manifestations of acromegaly. Endocrinol Metab Clin North Am 1992; 21: 597. https://doi.org/10.1016/S0889-8529(18)30204-4
StrubJ, Kern M, TürpJ: Curriculum Prothetik Quintessenz 2011; Band III, 851–857.
Copyright (c) 2022 Authors
This work is licensed under a Creative Commons Attribution 4.0 International License.